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There are three main types of antidepressant: Selective serotonin re-uptake inhibitors (SSRIs), Tricyclic antidepressants (TCAs) and Monoamine oxidase inhibitors (MAOIs). Treatment with antidepressants usually starts with a TCA or SSRI. It takes about two to three weeks for the medicines to start working, and four to six weeks for them to fully take effect. If you are elderly, it may take longer for antidepressants to start working, and up to eight weeks for them to work fully. Antidepressants often have to be taken for a long time, and it is important to come off them slowly to prevent side effects.

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Generic Celexa is used for treating depression.

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Generic Lexapro is used for treating depression and generalized anxiety disorder.

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Generic Paxil is used for treating depression or obsessive-compulsive disorder (OCD). It may be used to treat panic disorder, posttraumatic stress disorder (PTSD), generalized anxiety disorder or social anxiety disorder.

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Generic Zyprexa is used to treat the symptoms of psychotic conditions such as schizophrenia and bipolar disorder (manic depression).

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For adults with severe depression there is strong evidence that antidepressants are more effective than any other treatment. If depression is mild or moderate, psychotherapy alone may be sufficient, though even in this case, short-term antidepressant drug treatment or herbal therapy can help people get to the point where they can engage in therapy and get some exercise (which is also thought to help improve mood).