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Generic Nolvadex is the name of the drug whose scientific name is tamoxifen citrate. Tamoxifen citrate is a potent anti-estrogen used as an ancillary drug during cycle. It can also be used post cycle to restore natural testosterone production. The medication should be taken at the same time(s) each day to maintain an even level in your blood.

Tamoxifen: Mechanism of Action

When the tamoxifen molecule binds to the receptors, estrogen is blocked and cannot result in any type of action - therefore an anti-estrogen effect is exhibited. Nolvadex is used clinically in the treatment of breast cancer since many forms of breast cancer are responsive to the action of estrogen. Nolvadex blocks its actions and works as an effective treatment. Aside from direct treatment of breast cancer, it is used as a preventative measure for those with a genetic predisposition for breast cancer. A standard dosage of nolvadex on cycle as an anti-estrogen would be 10-30mg a day. The amount used would depend on what effect the user would like to elicit.

Nolvadex Warnings & Adverse Reactions

When they occur, the bone pain or disease flare are seen shortly after starting Nolvadex and generally subside rapidly. Loss of libido and impotence have resulted in discontinuation of tamoxifen therapy in male patients. The incidence of hot flashes (64% vs. 48%), vaginal discharge (30% vs. 15%), and irregular menses (25% vs. 19%) were higher with Nolvadex compared with placebo. A causal relationship has not been established; however, as an increase in the incidence of endometrial adenocarcinoma and uterine sarcoma has been noted in adults treated with Nolvadex continued monitoring of McCune-Albright patients treated with Nolvadex for long-term effects is recommended.

Additional positive effects of Nolvadex

Certain types of breast cancer require estrogen to grow. Tamoxifen is used to treat and prevent some types of breast cancer. Tamoxifen decreases the removal of the anticoagulant medicines nicoumalone and warfarin from the body and hence increases their anti-blood-clotting effect. Women taking anticoagulants in combination with tamoxifen should have their blood-clotting times regularly monitored, and your doctor may need to reduce the dose of your anticoagulant.